Scari.org Scari
Genomics |
Scari Genome Development: |
atomic force microscopy (AFM) |
Discoveries: RAPID EVOLUTION OF A PROTEIN IN-VITRO BY DNA SHUFFLING Our research is focused on the molecular mechanisms of genetic recombination, with the long-term objective being the reconstitution of in-vitro systems that accurately reproduce the cellular processes. We are characterizing the biochemical properties of proteins essential to homologous recombination, in prokaryotes, eukaryotes, and Archaea. These ideas are all accepted by the overwhelming bulk of scientists, with the possible exception of gradualism, which in its purest manifestation has been challenged by Goulds and Eldreges concept of punctuated equilibrium. The other ideas now form a set that can justifiably be called the fact of evolution. Transposons and Retrotransposons DNA shuffling is a method for in vitro homologous recombination of pools of selected mutant genes by random fragmentation and polymerase chain reaction (PCR) reassembly. Genetic recombination is the transfer of DNA from one organism to another. The transferred donor DNA may then be integrated into the recipient's nucleoid by various mechanisms. Through Transposon Technology and DNA shuffling a recombination in cell property occurs. Flp recombinase promotes site-specific DNA recombination in embryonic stem cells and transgenic swine. Broad Flp expression is compatible with normal development, suggesting that Flp can be used to catalyze recombination in most cell types. These properties indicate that Flp can be exploited to make prescribed alterations in both swine and primate genome -- to include the Homo Sapian Sapian.. |
Frolic
in Paradise Conclusion: Had the yeastie been inbued with cognition and science beyond natural selection they could have taken counter measures that would secure their fate, perserve the realm and continue their frolic. parson Carson Gallant Charoot |
Upon specific stimulation, cells in the G0 phase may re-enter the G1 phase. Note: Codes are under license and are owned with intellectual rights held by licensee
It's not been a bed of roses, we have had setbacks, and miss-steps; not all of our research has born usable fruit. An omnipresent dissapointment has been Large Offspring Syndrome; a condition that is now mitigated by massive doses of steroids and hormone therapy after delivery. For us at SCARI "life starts at conception and ends at birth," we have no interest in postnatal depression responsibilities.
Tagging Errors 1272 bases (including the stop codon) Tagging errors were responsible
for our mistaken assurance of success. The result of this miscalculation
has caused a reassessment of our original data. ccaat ttggtatatt atgtaaaaca ccacctaagg tgcttgttcg tcagatgccatttgtg gaaaggtttg aaagaccttc aggtgagaaa atagcattat gtgctgctga actaacctat ttatgttgga tgattacaca taacggaaca gcaatcaaga gagccacatt catgagctat aatactatca taagcaattc gctgagtttc gatattgtca ataaatcact ccagtttaaa tacaagacgc aataagcaac aattctggaa gcctcattaa agaaattgat tcctgcttgg gaatttacaa ttattcctta ctatggacaa aaacatcaat ctgatatcac tgatattgta agtagtttgc aattacagtt cgaatcatcg gaagaagcag ataagggaaa tagccacagt aaaaaaatgc ttaaagcact tctaagtgag ggtgaaagca tctgggagat cactgagaaa atactaaatt cgtttgagta tacttcgaga tttacaaaaa caaaaacttt ataccaattc ctcttcctag ctactttcat caattgtgga agattcagcg atattaagaa cgttgatccg aaatcattta aattagtcca aaataagtat ctgggagtaa taatccagtg tttagtgaca gagacaaaga caaccgatag taggcacata tacttcttta gcgcaagggg taggatcgat ccacttgtat atttggatga atttttgagg aattctgaac cagtcctaaa acgagtaaat aggaccggca attcttcaag caataaacag gaataccaat tattaaaaga taacttagtc agatcgtaca ataaagcttt gaagaaaaat gcgccttatt caatctttgc tataaaaaat gtcccaaaat ctcacattgg aagacatttg atgacctcat ttctttcaat gaagggccta acggagttga ctaatgttgt gggaaattgg agcgataagc gtgcttctgc cgtggccagg acaacgtata ctcatcagat aacagcaata cctgatcact acttcgcact agtttctcgg tactatgcat atggcccaat atcaaaggaa atgatagcat tgaaggatga gactaatcca attgaggagt ggcagcatat agaacagcta aagggtagtg ctgaaggaag catacgatac cccgcatgga atgggataat atcacaggag gtactagact acctttcatc ctacataaat agacgcatat aa
Subsequent typing has not been so error prone. DNA at work: With Scientific Relish we at SCARI Genome have sliced through the helix eliminating the skree and clutter of normal plodding research, adding a level of excitement and intensity of our research, research that would, under normal labrotory norms, be droll and boring. Tagger reorganization: Taggers employed for sequence annotation have been reorganized into a phalanx of devoted genome sequencing technicians. |